Sparkling white sands stretch along Panama City Beach's shoreline, bordered by vibrant resort architecture and the deep blue Gulf of Mexico, creating a striking coastal panorama. | Houfy — Book Direct

Panama vacation rentals

Vacation rentals in Panama by owner — compare homes, condos and cabins, message verified hosts, and book direct with no service fees.

Panama draws adventure-seekers to the Panama Canal, the rainforests of Soberania National Park, and the coffee plantations of Boquete. Visitors come to surf at Santa Catalina, explore the San Blas Islands, and bird-watch in the highlands. Houfy connects travelers directly with Panamanian hosts. Discover homes in Panama City, mountain cabins in Boquete, and beachfront properties in Bocas del Toro. The dry season from mid-December to mid-April is best for visiting the Pacific coast.

Top-Rated Vacation Homes in Panama

Browse the highest rated vacation properties in Panama.

Charming Spacious Boutique Studio in Casco Viejo

0 bd·1 ba
5· 454

$385.00 USD total for 3 nights

Sep 21 – 24, 2026

A Perfect Place in El Casco Viejo
Patty’s Casitas is your best choice if you are planning to visit Panama. I stayed in the studio condo in the Casco Viejo from 22nd of September to the 24th, spent four days in Boquete and then returned to el studio from 28th until 1st October. I do have a lot of memories in El Casco Viejo, I am from here. I moved to this area in 1968, attended Simon Bolivar elementary school from 1971 until 1978, first communion in La Catedral in 1975, confirmation in La Merced in 1987 and wedding in La Merced in 2004. I am now an US Army servicemember retiree (after 26 years) and travel to Panama every six months to visit my mother who still lives in El Casco Viejo. Patty and Rudy are the people you want to talk if you are planning a trip to Panama and El Casco Viejo. They are great host and people that would do the ultimate to make your stay in Panama a nice memory. The studio room is so comfortable, clean and quiet that will make you believe you are by yourself in this building. El Casco Viejo is loud per nature because of all the new remodeling, restaurants, cars and people but the studio room is located in the back of the building and you will not hear anything. Rudy and Patty accommodated me between their busy schedule to ensure that I had no concerns with the room or my stay in my country. From the studio, I walked all over El Casco Viejo with my mother and it is amazing how it has changed from a quiet place back in the days to one of most visited places in Panama. I recommend Patty’s Casitas to anyone. In conclusion, everything is perfect in this place, A great place to stay!!! Kenny Rivera US Army (Ret) PS. I forgot the delicious coffee that you could make in the studio to start the day with smile and energy.
k. r.

Stunning CASCO VIEJO 2 bdr/2 bth Loft & Balcony

2 bd·2 ba
5· 283

$520.00 USD total for 3 nights

Sep 21 – 24, 2026

Stairway to Heaven
Led Zeppelin may have got there first with this title (in 1971) but it well describes the Loft where we stayed for a week in Casca Viejo, Panama City. And the first line of the lyrics is uncannily relevant: "There's a lady who's sure all that glitters is gold. And she's buying a stairway to heaven." That lady is Patty. Right from our first enquiry for our Anniversary holiday, Patty was responsive to all our questions and advised us well on all aspects of our stay, including when we were let down by our next accommodation in Farallon. We cannot fault her, even though some may be a little wary of paying upfront by international bank transfer - the excellent reviews for her business reassured us that we had nothing to worry about. We had the top floor Loft accessed by several flights of long stairs. Even though one of us suffers a bad back, the stairs were manageable. Rudy was extremely helpful in taking our heavy suitcases up and down - he made it easy for us as we are getting on in years. Inside the one bedroom loft, we were impressed by the layout (two bathrooms, one en suite and one serving the living space and kitchen-diner), the decor including the lovely and huge replica clock from Kensington Station in London, and the amenities. In this last category, Patty gave us a mobile phone with local Sim to use to contact her if necessary, as well as free use for local calls on a landline. We were so pleased that the Loft is in the old town, now being lovingly restored to its former glory. The view from our balcony was so relaxing; and is a lovely place for breakfast. The sleeping area is on an upper mezzanine floor - you have to have a head for heights. We could go on. We thoroughly recommend Patty's Casitas, especially if, like us, you do not like modern hotels or even modern cities.

Beautiful Upscale Bay View Condo by the Causeway

1 bd·1 ba
5· 196

$465.00 USD total for 4 nights

Sep 21 – 25, 2026

Our Home Away from Home
Although this vacation was not our first outside the USA, it was our first time in Panama and our first time using VRBO. Many thanks must go to my wife for finding Patty's Casitas among the hundreds of choices that a vacationer can discover on-line. I am usually not ( ok never) the vacation planner for our trips which I guess is why I am writing this review. I have read a few of the reviews on here and wholeheartedly agree that Patty's Condo property was one of the nicest places we have ever stayed. While there is great appeal for staying in the ritzy hotels for the glamorous nightlife, the Condo was a breath of fresh air far enough away from the "maddening" crowd, but a short taxi ride from anywhere you wanted to go. As mentioned in other reviews our condo was equipped with everything a person needed for a most pleasant stay. House rules are posted so there are no misunderstandings and a binder with answers for almost all your questions that you may have during your stay. Our trip to Panama got off to a rough start by being 8 hours late due to airline so instead of arriving in midafternoon, we arrived after 10 p.m. and closer to 11:30 p.m. before arriving at the condo. Even though the hour was late Patty's Husband, Rudy, was there at the condo waiting to check us in and make us feel right at home. He thoroughly showed us the condo and how to operate the AC, and TVs and kitchen appliances. Both Patty and Rudy were always available via phone if we needed information about shopping or dining or touring as Rudy is also a licensed Tour Guide and as far as my wife and I are concerned, the best tour guide we have ever encountered anywhere. Both TGI Fridays and the Balboa Yacht Club were within walking distance from the condo and the food was great. Although we generally like to go to different places each year, we have already decided that we are going back to Panama and when we do our first stop will be with Patty and Rudy.
Stay January 2016

Emerald Retreat

2 bd·2 ba
5· 9

$770.00 USD total for 3 nights

Sep 21 – 24, 2026

From the easy checkin to the beach views from the balcony it was a special treat to stay here. Carts are available to help with luggage. Parking was easy and came with the rental. I spent all of my time going from the beautiful beach to one of the pools to relaxing in the condo. Restaurant is on site also. All needs were met in the kitchen. The bed was very comfortable. Would definitely visit again
R. · Stay March 2023

Recommended Homes in Panama

Handpicked properties we think you'll love in Panama.

Gemini II

3 bd·3 ba
4.5· 18

$945.00 USD total for 3 nights

Sep 21 – 24, 2026

Why visit Panama

Discover what makes Panama a perfect vacation rental destination.

Stunning Pacific Beaches

Explore pristine beaches like Playa Venao.

Just a 5-hour drive from Panama City, Playa Venao offers excellent surfing conditions. Relax with a cocktail at one of its beachfront bars while enjoying panoramic ocean views.

Historic Panama Canal

Engineering marvel over 100 years old.

Visit the Miraflores Visitor Center, just 20 minutes from Panama City. Witness massive ships navigate through this iconic waterway—an engineering feat since 1914.

Diverse Rainforests

Discover Soberanía National Park’s wildlife.

Located 25 kilometers from Panama City, this park boasts 525 bird species. Book a guided tour to spot capuchin monkeys and toucans in their natural habitat.

Vibrant Local Culture

Explore Panama City's Casco Viejo district.

This UNESCO site features colonial architecture with hip bars and cafés. Visit Teatro Nacional de Panamá for local art and performances, only a 15-minute walk from the Presidential Palace.

Where to stay in Panama

The best areas and neighborhoods for your vacation rental in Panama.

Casco Viejo

A UNESCO World Heritage site, Casco Viejo charms with cobblestone streets, vibrant murals, and rooftop bars. It's a haven for history enthusiasts.

Best for: history buffs, nightlife lovers, culture seekers

Boquete

Nestled in the Chiriquí Highlands, Boquete is known for its cool climate, coffee plantations, and adventures like zip-lining. Ideal for nature lovers.

Best for: adventurers, nature lovers, coffee enthusiasts

Bocas del Toro

Bocas del Toro is famed for its crystal-clear waters, snorkeling spots, and lively Caribbean culture. Accessible by flight from Panama City.

Best for: beachgoers, snorkelers, nightlife lovers

El Cangrejo

A bustling neighborhood with trendy restaurants and boutique hotels, El Cangrejo is known for its lively streets and culinary delights.

Best for: foodies, urban explorers, shoppers

Find Panama vacation rentals that suit your style

Condos, villas, studios and more — pick the kind of Panama vacation rental you want, then book it direct with the host.

Panama vacation rentals with free WiFi, hot tub or air conditioning

Free WiFi, hot tub, air conditioning and more — every Panama vacation rental here is listed by a verified host and bookable direct, with the price the host set.

Top attractions in Panama

All within driving distance of Panama vacation rentals.

Panama Canal

Visit the Miraflores Locks to see ships navigating the canal. · 10 km from city center

Soberanía National Park

This park is a haven for birdwatchers with over 500 species. · 30 km from city center

Casco Viejo

Explore colonial architecture and vibrant street art. · 5 km from city center

San Blas Islands

A collection of over 300 islands offering pristine beaches. · 112 km from city center

Biomuseo

Designed by Frank Gehry, this museum showcases Panama's biodiversity. · 12 km from city center

Mercado de Mariscos

Try fresh ceviche at Panama City's seafood market. · 6 km from city center

Best Time to Visit Panama

Best months to visit are December to April with warm temperatures ranging from 85-90°F and less rain. Ideal for beach lovers seeking sunny skies.

The best time to visit Panama is January to March, when the weather is at its best. For lower prices and fewer crowds, September to November is the best time to book.

Best weatherJan – Mar
Best valueSep – Nov

SepNow

86°F30°C

Rainfall High

Demand Low

Oct

86°F30°C

Rainfall High

Demand Low

Nov

87°F31°C

Rainfall High

Demand Low

Dec

88°F31°C

Rainfall Moderate

Demand Mid

Jan

89°F32°C

Rainfall Low

Demand Peak

Feb

90°F32°C

Rainfall Low

Demand Peak

Mar

91°F33°C

Rainfall Low

Demand Peak

Apr

91°F33°C

Rainfall Moderate

Demand Peak

May

89°F32°C

Rainfall High

Demand Mid

Jun

87°F31°C

Rainfall High

Demand Mid

Jul

86°F30°C

Rainfall High

Demand Mid

Aug

86°F30°C

Rainfall High

Demand Mid

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