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Durham vacation rentals

Vacation rentals in Durham by owner — compare homes, condos and cabins, message verified hosts, and book direct with no service fees.

Durham, the City of Medicine, is home to Duke University, the American Tobacco Campus, Sarah P. Duke Gardens, and the Durham Performing Arts Center. The city attracts visitors with its vibrant arts scene, sports events at Cameron Indoor Stadium, the tasty offerings at the Durham Farmers' Market, and historic tours in the Ninth Street District. Houfy connects you directly with local hosts in Durham. Choose from downtown lofts, historic homes in Trinity Park, or family-sized residences near Chapel Hill and Raleigh. Look out for events like the Full Frame Documentary Film Festival for cultural insights.

Top-Rated Vacation Homes in Durham

Browse the highest rated vacation properties in Durham.

Kamp Koral Raleigh - Near RDU, Brier Creek, RTP

3 bd·4 ba
5· 78

$722.00 USD total for 3 nights

Oct 13 – 16, 2026

Great property!
My family of 5, including some small children, stayed at Kamp Koral for a weekend to visit family we have in the area. The property was very well-maintained, the location was perfect for us, and was overall a great experience.
W. J. · Stay March 2024

(The Bull & Bean) Duke, Eco+ Espresso Bar, Bike

3 bd·2 ba
5· 28

$970.36 USD total for 3 nights

Oct 18 – 21, 2026

Wonderful home away from home for healing.
I had an excellent stay at this beautiful home while recovering from surgery, and I honestly couldn’t have asked for a better place to heal. The space was clean, quiet, and thoughtfully set up for longer stays, which made day-to-day living easy and comfortable. The peaceful atmosphere allowed me to truly rest and focus on recovery. The home had everything I needed, from a very comfortable bed to a well-equipped kitchen, and the host was kind, responsive, and went out of her way to provide, bring by, and even order a back rest pillow for us. Staying here gave me a sense of stability and calm during a time when that mattered most. I’m very grateful for such a supportive and comfortable, well decorated, and well supplied place and would highly recommend it to anyone needing a longer stay, especially during recovery.
Kimberly R. · Stay January 2026

New Home w/Game Room near RDU airport/Duke/UNC/RTP

3 bd·2½ ba
4.89· 100

$692.00 USD total for 3 nights

Oct 27 – 30, 2026

The Dancing Daisy Raleigh

2 bd·2½ ba
5· 40

$650.00 USD total for 3 nights

Oct 18 – 21, 2026

Lovely Rental
I loved staying at The Dancing Daisy. It was clean, quiet and had all of the extras to make your stay comfortable. We were able to go out the front door and take long walks on the sidewalks around the neighborhood. Very pretty and safe area. Easy drives to all of the places we wanted to visit. Duke University and the beautiful Botanical Gardens there. The Lucky Strike Factory Restaurants were fun to visit. Grocery store was close. There is absolutely not one thing to complain about on this trip! It was perfect!
C. U. · Stay April 2025

Duke Forest Zen Treehouse - pool table, decks

3 bd·2 ba
5· 62

$1,106.63 USD total for 5 nights

Dec 14 – 19, 2026

The treehouse was incredible & a beautiful haven for a family birthday celebration in the snow. Joe made sure we had wood for the fireplace & more salt/sand if needed. The house was perfect for games & cooking with a fully equipped beautiful kitchen. The views were picturesque as the snow fell. It was extra cozy & the beds were just right! In addition, Joe was generously accommodating by letting us take our time checking out. Our family event was made even more memorable because of this magical location & abundant hospitality! We will definitely come again!!
S. · Stay February 2026

Lush 3BD/2.5BA, Pet-Friendly, Tranquil Retreat

3 bd·2 ba
5· 2

$768.64 USD total for 3 nights

Oct 31 – Nov 3, 2026

The place was clean and cozy with amenities as described. Though there is additional documents and paperwork to complete than usual, the host was professional and responsive. I was there under strenuous circumstances and did not spend a lot of time at the property, except to sleep. The time spent was cozy, quiet and we felt safe during our stay.
F. · Stay January 2024

Cozy 3BD Stay | BBQ & Yard | Mins to Duke/Downtown

3 bd·2 ba
5· 4

$672.00 USD total for 3 nights

Oct 19 – 22, 2026

This house was much nicer than the houses surrounding it, but I never once felt uncomfortable or was bothered by anyone. It has a private driveway and the inside is stunning and looks exactly like the pictures with a nice backyard. Very clean, modern, and roomy. The location was very quiet and close to Durham. Krishanthi was very nice and reached out multiple times to me to check in.
N. · Stay July 2025

Private Wooded Retreat in the Center of Town

1 bd·1 ba
4.88· 56

$391.58 USD total for 3 nights

Oct 13 – 16, 2026

Ragini and her husband were incredibly kind and accommodating, even welcoming me after delays on Airbnb’s side, something I deeply appreciated. Communication was responsive across time zones, and the property itself is peaceful and beautiful. Scott, who helped manage the space while the hosts were away, was also kind and attentive. The space is more of a retreat-style setup than a full home or long-term stay. There’s no dining area or full kitchen, but there is a coffee bar with some prep space, a Nespresso machine, microwave, and mini fridge (without a freezer), so meals need to stay simple. The space was very clean, the bed was super comfortable, and the bidet was a lovely surprise! Overall, I felt safe and cared for, which mattered most. The setup was perfect for rest and short stays, though it might be harder to manage for longer visits. I really enjoyed myself! If you’re a nature lover who values peace and wants a quiet spot within reach of the city, this is the place.
I. · Stay August 2025

Recommended Homes in Durham

Handpicked properties we think you'll love in Durham.

Downtown/Duke. Sleeps large group/family

4 bd·3 ba
4.76· 50

$862.20 USD total for 3 nights

Oct 18 – 21, 2026

$667.50 USD total for 3 nights

Nov 1 – 4, 2026

$2,857.50 USD total for 14 nights

Nov 1 – 15, 2026

$2,333.87 USD total for 3 nights

Apr 11 – 14, 2027

$755.17 USD total for 3 nights

Oct 13 – 16, 2026

$663.50 USD total for 3 nights

Oct 13 – 16, 2026

Why visit Durham

Discover what makes Durham a perfect vacation rental destination.

Duke University

Top-ranked university with beautiful campus.

Visit the iconic Duke Chapel and Sarah P. Duke Gardens. The campus is just 3 miles from downtown Durham.

Culinary Hotspot

Thriving food scene with diverse options.

Explore restaurants like Dame’s Chicken & Waffles on Main St. or visit The Durham Food Hall, a 5-minute drive from City Center.

Nasher Museum of Art

Features global art exhibitions and events.

Located at Duke University, just 2.5 miles from downtown, it's the cultural heart of Durham with world-renowned collections.

American Tobacco Campus

Historic site turned vibrant community hub.

Takes you back in time while offering modern eateries and shops, located just steps from the Durham Bulls Athletic Park.

Where to stay in Durham

The best areas and neighborhoods for your vacation rental in Durham.

Brightleaf District

Known for its historic tobacco warehouses transformed into trendy shops and eateries, it's a central hub for nightlife and local culture.

Best for: nightlife, shopping, dining

American Village

Popular among families, this neighborhood offers scenic parks and suburban comfort just 4 miles north of downtown.

Best for: families, parks, suburban lifestyle

Trinity Park

With beautiful homes and tree-lined streets, it's ideal for those who enjoy charming walks block from Duke's East Campus.

Best for: charming walks, historic homes

Ninth Street

Affectionately called Durham’s ‘second downtown’, it's filled with indie boutiques and cafes, just west of Duke’s East Campus.

Best for: shopping, cafes, youthful vibe

Find Durham vacation rentals that suit your style

Vacation homes, condos, townhomes and more — pick the kind of Durham vacation rental you want, then book it direct with the host.

Durham vacation rentals with free WiFi, hot tub or air conditioning

Free WiFi, hot tub, air conditioning and more — every Durham vacation rental here is listed by a verified host and bookable direct, with the price the host set.

Top attractions in Durham

All within driving distance of Durham vacation rentals.

Museum of Life and Science

This interactive museum offers outdoor exhibits like the Dinosaur Trail, located 5 miles from downtown. · 5 miles

Durham Bulls Athletic Park

Home to the famous minor league baseball team, it's right in downtown, next to the American Tobacco Campus. · 1 mile

Eno River State Park

Provides over 4,000 acres of trails and scenic river views, just 10 miles northwest of downtown. · 10 miles

Carolina Theatre

A historic venue for live performances and films located right in the heart of downtown Durham. · 0.5 miles

Durham Food Hall

Features a variety of local vendors offering diverse eats, located 1.5 miles from the city center. · 1.5 miles

Bennett Place

Site of the largest surrender of Confederate soldiers, it's just 5 miles west of downtown. · 5 miles

Getting to and around Durham

Durham is accessible by air and road, with local transit options for easy exploration.

Airports
RDU INTERNATIONAL AIRPORT
Located 17 miles southeast, serving as the main airport for the region.
Driving
I-40 AND I-85
These major interstates connect Durham to Raleigh, Chapel Hill, and other nearby cities.
Public Transit
GoDurham
Local buses offer convenient routes throughout the city and to nearby areas.

Similar vacation rentals near Durham

Homes within 60 miles of Durham, from verified hosts.

Newly renovated, clean, convenient, quiet & comfy

2 bd·2 ba
5· 519

$412.50 USD total for 3 nights

Oct 13 – 16, 2026

$1,155.00 USD total for 3 nights

Oct 13 – 16, 2026

The Perky Pineapple Raleigh ; One-Level

2 bd·2 ba
5· 65

$603.00 USD total for 3 nights

Oct 13 – 16, 2026

Carolina House

3 bd·2 ba
4.85· 130

$622.65 USD total for 3 nights

Oct 13 – 16, 2026

Lazy Lemon Cary; Walk to Koka Booth

2 bd·2 ba
5· 51

$624.00 USD total for 3 nights

Oct 18 – 21, 2026

Crowe's Nest, Lakefront Near Golf & Fort Bragg

3 bd·2½ ba
5· 50

$1,402.50 USD total for 3 nights

Oct 13 – 16, 2026

La Casita Cary- 1/2 mi. walking distance to shops!

4 bd·2 ba
5· 3

$11,047.00 USD $8,329.00 USD total for 60 nights

Dec 31, 2026 – Mar 1, 2027

$468.56 USD total for 3 nights

Oct 13 – 16, 2026

Pop-Of-Color - Loft!

1 bd·1 ba

$288.60 USD total for 3 nights

Oct 13 – 16, 2026

Floating Flamingo Cary; Walk to Greenway

2 bd·2½ ba
5· 15

$682.00 USD total for 3 nights

Oct 13 – 16, 2026

Cute & Cozy - Poppy Loft

1 bd·1 ba

$338.60 USD total for 3 nights

Oct 13 – 16, 2026

Spacious 4BR Home w/ Game Room and Backyard Oasis

4 bd·2 ba
5· 37

$1,179.00 USD total for 3 nights

Oct 13 – 16, 2026

Explore near Durham

Cities and towns within driving distance of Durham, each bookable direct with the host.

  • Direct with the host

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Quick answers about booking vacation rentals in Durham and what direct booking on Houfy actually means.

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